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Sure. I do it every day.
On my SQL server, I wrote a DTS script to mirror the JodoHost database to my SQL server at my office. Then I scheduled the script to run each evening.
Then, I back up my office SQL server using normal backup tools.
Here's links for documentation: http://msdn.microsoft.com/library/default.asp?url=/library/en-us/dtssql/dts_tools_wiz_8vsj.asp