There is a very odd error that I have never had in the past about the registry coming, and I am going to reboot it in order to attempt resolution.
The reboot will be happening in 5-8 minutes I estimate, working to try resolution without a reboot. (Note sites ARE up and running)
rebooting now.
rebooted and IIS and all back up now.
OK the original error is also fixed now as well, so we are back in proper condition now.