Windows & Linux

I have a website that I am building with php/mysql and plan on putting on a Linux server. However, the website will have a sub-domain that will contain a classic ASP application, Can I create the sub-domain on a windows server and change the DNS setting on the Linux server to point to the windows server or will the domains conflict with each other?

If I have to put the entire site on a Windows server, does the PHP on your windows server allow the use of PDO for php/mysql data access?

Windows allows PDO data access yes, windows allows fully custom php.ini, at least on 2003. I need to check if new 2008 R2 allows or not, 2008 did not.

Without the domain being the service domain there’s not really a way to make a subdomain of one on linux and main on windows(or reverse)